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Type: 
Journal
Description: 
We provide novel evidence that human melanoma cell lines (M10, M14, SK-MEL28, SK-MEL93, 243MEL, 1074MEL, OCM-1, and COLO38) expressed, at mRNA and protein levels, either Ca2+-independent phospholipase A2 (iPLA2) or cytosolic phospholipase A2 (cPLA2) and its phosphorylated form. Normal human melanocytes contained the lowest levels of both PLA2s. Cyclooxygenase-1 and-2 (COX-1 and COX-2) were also expressed in cultured tumor cells as measured by Western blots. The most pronounced overexpression of iPLA2 ...
Publisher: 
Elsevier
Publication date: 
31 Oct 2008
Authors: 

Mariagrazia Rita Scuderi, Carmelina Daniela Anfuso, Gabriella Lupo, Carla Motta, Loriana Romeo, Liliana Guerra, Alessandro Cappellani, Nicola Ragusa, Giuseppina Cantarella, Mario Alberghina

Biblio References: 
Volume: 1781 Issue: 10 Pages: 635-642
Origin: 
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids