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Type: 
Journal
Description: 
We present the design, fabrication, and testing of a low-cost, miniaturized detection system that utilizes chemiluminescence to measure the presence of adenosine triphosphate (ATP), the energy unit in biological systems, in water samples. The ATP–luciferin chemiluminescent solution was faced to a silicon photomultiplier (SiPM) for highly sensitive real-time detection. This system can detect ATP concentrations as low as 0.2 nM, with a sensitivity of 79.5 A/M. Additionally, it offers rapid response times and can measure the characteristic time required for reactant diffusion and mixing within the reaction volume, determined to be 0.3 ± 0.1 s. This corresponds to a diffusion velocity of approximately 44 ± 14 mm2/s.
Publisher: 
MDPI
Publication date: 
17 Jun 2024
Authors: 

Giuseppe E Capuano, Domenico Corso, Roberta Farina, Gianni Pezzotti Escobar, Giuseppe A Screpis, Maria Anna Coniglio, Sebania Libertino

Biblio References: 
Volume: 24 Issue: 12 Pages: 3921
Origin: 
Sensors