Mono-metallic and bi-metallic Palladium and Platinum nanoparticles find important applications for sensing detection, catalysis, hydrogen storage, fuel cell etc. However, the success of such technologies is subjected to the development of simple, versatile, low-cost, high-throughput methods for the production of the nanoparticles with desired sizes or composition. In particular, we present a laser-assisted synthesis method for the production of stable mono- and bi-metallic Pd and Pt nanoparticles. It is based on the nanosecond-pulsed laser ablation, in liquid environment, of pure Pd or Pt targets and of PtPd composite target at different ablation times. We characterized nanoparticles’ morphology and crystalline structure by Transmission Electron Microscopy, Selected Area Electron Diffraction, X-Ray Diffraction and Energy Dispersive X-Ray measurements. In particular, the microscopic analysis showed that the average …