The presence of pharmaceuticals, such as non-steroidal anti-inflammatory drugs (NSAIDs) in the aquatic environment represents a worldwide threat. NSAIDs are considered “emerging contaminants” of water since the traditional methods are not designed to efficiently remove them. Aiming to overcome the limits of the conventional wastewater treatment plants, we propose molecularly imprinted polymers (MIPs) as valid tools for selective adsorption and removal of these drugs from water. In particular, in this work, we have prepared diclofenac-selective MIP by a simple bulk polymerization process. After the characterization of the synthetized polymers, the binding abilities were evaluated in detail through the adsorption of diclofenac in aqueous solution and compared with the abilities of a corresponding non-imprinted polymer used as a reference. Thanks to the imprinting effect, the prepared MIP adsorbs with extreme …